Scandiv I
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Primary results have been published in JAMA1
One-year results have been published in BJS2
Fulltext article JAMA Editorial JAMA
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Acute diverticulitis is a common disease in the western world. Acute diverticulitis is a common disease in the western world. Perforation of the acute diverticulitis with peritonitis is a feared complication and standard treatment (primary sigmoid resection) has high mortality and morbidity. Several cohort studies have reported a lower mortality and morbidity when treated with laparoscopic lavage instead of sigmoid resection.
SCANDIV started in 2010 as a randomized multicenter trial in Scandinavia comparing primary sigmoid resection with laparoscopic lavage as treatment for acute perforated diverticulitis. In total 199 patients were included over a period of 4 years. The main end-point was severe postoperative complications within 90-days.
Primary results were published in JAMA in 2015 and one-year results in the British Journal of Surgery in 2017.1,2 Long term results are being collected.
1. Schultz JK, Yaqub S, Wallon C, Blecic L, Forsmo HM, Folkesson J, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial. 1
JAMA 2015; 314: 1364-75
2. Schultz JK, Wallon C, Blecic L, Forsmo HM, Folkesson J, Buchwald P, et al. One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis.
Br J Surg. 2017:n/a-n/a.