Scandiv I has been completed in 2014 and long term follow-up has been published.
10-year follow up will be performed within the next year.
Scandiv II has concluded inclusion and data is currently being analysed.
For further information click links above.
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Informasjon til deltakere i Scandiv studien
SCANDIV II is and exploratory, prospective, longitudinal, non-interventional, multicentre study for the evaluation of treatment of patients with acute complicated diverticulitis. We have chosen the Hinchey Classification system (table 1) for description. The treatment of complicated diverticulitis is controversial. Whereas Scandinavian surgeons usually adhere to a watch and wait strategy after a conservatively treated episode of complicated diverticulitis, several international guidelines recommend an elective operation for the majority of these patients.
The aim of this study is to explore the current treatment strategies in patients with acute complicated diverticulitis according to the Hinchey classification in Swedish and Norwegian hospitals and to assess failure rates during a one-year period. Secondly to evaluate the course of the disease for patients with complicated diverticulitis managed without resection surgery. We will also study the quality of life for all patients with complicated diverticulitis.
Table 1. Hinchey classification for complicated perforated diverticulitis
I: Pericolic abscess
II: Distant/pelvic abscess
III: Generalized purulent peritonitis
IV: Faecal peritonitis
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Results of Scandiv I:
Primary results have been published in JAMA 1
One-year results have been published in BJS 2
Fulltext article JAMA Editorial JAMA
Fulltext article 1year follow up BJS
Fulltext article 5-year follow up JAMA surgery 3
Fulltext article riskfactors for failure BJS 4
1. Schultz JK, Yaqub S, Wallon C, Blecic L, Forsmo HM, Folkesson J, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial. JAMA 2015; 314: 1364-75.
2. Schultz JK, Wallon C, Blecic L, Forsmo HM, Folkesson J, Buchwald P, et al. One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis. Br J Surg 2017;104(10): 1382-1392.
3. Azhar N, Johanssen A, Sundström T, Folkesson J, Wallon C, Kørner H, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial. JAMA Surg 2021;156(2): 121-127.
4. Azhar N, Lambrichts D, Lange J, Yaqub S, Øresland T, Schultz J, et al. Laparoscopic lavage for Hinchey III perforated diverticulitis: factors for treatment failure in two randomized clinical trials. Br J Surg 2023;110(7): 846-851.