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Primary results have been published in JAMA 1
One-year results have been published in BJS 2
Fulltext article JAMA Editorial JAMA
Fulltext article BJS
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Acute diverticulitis is a common disease in the western world. Perforation of the acute diverticulitis with peritonitis is a feared complication and standard treatment (primary sigmoid resection) has high mortality and morbidity. Several cohort studies have reported a lower mortality and morbidity when treated with laparoscopic lavage instead of sigmoid resection.
SCANDIV started in 2010 as a randomized multicenter trial in Scandinavia comparing primary sigmoid resection with laparoscopic lavage as treatment for acute perforated diverticulitis. In total 199 patients were included over a period of 4 years. The main end-point was severe postoperative complications within 90-days.
Primary results were published in JAMA in 2015 and one-year results in the British Journal of Surgery in 2017.1,2 Long term results are being collected.
- Schultz JK, Yaqub S, Wallon C, Blecic L, Forsmo HM, Folkesson J, et al. Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: The SCANDIV Randomized Clinical Trial.
JAMA 2015; 314: 1364-75. - Schultz JK, Wallon C, Blecic L, Forsmo HM, Folkesson J, Buchwald P, et al. One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis.
Br J Surg. 2017:n/a-n/a.